Anti-H_CCR8 hIgG1 Reference Antibody, Defucosylation (BMS-986340)

Expression System	CHO
Aggregation	< 5% as determined by SEC-HPLC
Purity	> 95% as determined by SDS-PAGE
Species Reactivity	Human
Clone	Defucosylated,BMS-986340
Source/Isotype	Monoclonal Human IgG1
Application	Flow Cytometry; Bioassay; Bioactivity-ELISA
Specificity	Detects CCR8
Gene	CCR8
Other Names	CY6; TER1; CCR-8; CKRL1; CDw1 98; CMKBR8; GPRCY6; CMKBRL2;
	CC-CKR-8
Gene ID	1237
Background	CCR8, also known as ChemR1, TER1, and CKR-L1, belongs to the beta chemokine receptor family. It is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. CCR8 is expressed on some subsets of T cells, monocytes, macrophages, eosinophils, thymocytes, Langerhans cells, neurons, and vascular smooth muscle cells. Binding with its ligand CCL1, CCR8 plays a role in the regulation of monocyte chemotaxis and thymic cell apoptosis. It has been reported that CCR8 is also a receptor for CCL18. CCR8 is also believed to be an alternative coreceptor to CD4 for HIV-1 infection.
Storage	Store at 2-8°C short term (1-2 weeks). Store at ≤ -20°C long term.Avoid repeated freeze-thaw.
Formulation	Phosphate-buffered solution, pH 7.2-7.4.
Endotoxin	< 1 EU/mg, determined by LAL gel clotting assay

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Anti-H_CCR8 hIgG1 Reference Antibody, Defucosylation (BMS-986340)

Product info

Cat.No：GM-53822MAB

Product：Anti-H_CCR8 hIgG1 Reference Antibody, Defucosylation (BMS-986340)

Cat. No. & Size

GM-53822MAB-1mg / 1 mg

GM-53822MAB-5mg / 5 mg

GM-53822MAB-25mg / 5 mg * 5 vials

GM-53822MAB-50mg / 50 mg

GM-53822MAB-100mg / 50 mg * 2 vials

Description️

Expression System	CHO
Aggregation	< 5% as determined by SEC-HPLC
Purity	> 95% as determined by SDS-PAGE
Species Reactivity	Human
Clone	Defucosylated,BMS-986340
Source/Isotype	Monoclonal Human IgG1
Application	Flow Cytometry; Bioassay; Bioactivity-ELISA
Specificity	Detects CCR8
Gene	CCR8
Other Names	CY6; TER1; CCR-8; CKRL1; CDw1 98; CMKBR8; GPRCY6; CMKBRL2;
	CC-CKR-8
Gene ID	1237
Background	CCR8, also known as ChemR1, TER1, and CKR-L1, belongs to the beta chemokine receptor family. It is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. CCR8 is expressed on some subsets of T cells, monocytes, macrophages, eosinophils, thymocytes, Langerhans cells, neurons, and vascular smooth muscle cells. Binding with its ligand CCL1, CCR8 plays a role in the regulation of monocyte chemotaxis and thymic cell apoptosis. It has been reported that CCR8 is also a receptor for CCL18. CCR8 is also believed to be an alternative coreceptor to CD4 for HIV-1 infection.
Storage	Store at 2-8°C short term (1-2 weeks). Store at ≤ -20°C long term.Avoid repeated freeze-thaw.
Formulation	Phosphate-buffered solution, pH 7.2-7.4.
Endotoxin	< 1 EU/mg, determined by LAL gel clotting assay