Cat. No： GM-87786AB
Product： Anti-IL-23R hIgG1 Antibody(5D4)
Cat. No： GM-87786AB
Product： Anti-IL-23R hIgG1 Antibody(5D4)
GM-87786AB-10 10 μg
GM-87786AB-100 100 μg
GM-87786AB-1000 1 mg
Species Reactivity | Human; |
Clone | 5D4 |
Source/Isotype | Monoclonal human IgG1, κ |
Application | Flow cytometry |
Specificity | Detects IL-23R |
Gene | IL-23R |
Gene ID | 149233 (human) |
Background | Binding of 5D4 monoclonal antibody to IL-23R and il-23αil-12β heterodimeric ligands. IL-23R, as a receptor for IL-23 cytokines, mediates the IL-23 signaling pathway, activates JAK-STAT signaling, and promotes the proliferation and differentiation of Th17 cells. The IL-23/IL-23R signaling pathway plays an important role in promoting chronic inflammation and autoimmunity. Abnormal activation can lead to inflammatory cell infiltration, tissue damage and pathological changes. |
Storage | Store at 2-8℃ short term (1-2 weeks).Store at ≤ -20℃ long term. Avoid repeated freeze-thaw. |
Formulation | Phosphate-buffered solution, pH 7.2. |
Endotoxin | < 1 EU/mg, determined by LAL gel clotting assay |
Cat. No： GM-87786AB
Product： Anti-IL-23R hIgG1 Antibody(5D4)
GM-87786AB-10 10 μg
GM-87786AB-100 100 μg
GM-87786AB-1000 1 mg
Species Reactivity | Human; |
Clone | 5D4 |
Source/Isotype | Monoclonal human IgG1, κ |
Application | Flow cytometry |
Specificity | Detects IL-23R |
Gene | IL-23R |
Gene ID | 149233 (human) |
Background | Binding of 5D4 monoclonal antibody to IL-23R and il-23αil-12β heterodimeric ligands. IL-23R, as a receptor for IL-23 cytokines, mediates the IL-23 signaling pathway, activates JAK-STAT signaling, and promotes the proliferation and differentiation of Th17 cells. The IL-23/IL-23R signaling pathway plays an important role in promoting chronic inflammation and autoimmunity. Abnormal activation can lead to inflammatory cell infiltration, tissue damage and pathological changes. |
Storage | Store at 2-8℃ short term (1-2 weeks).Store at ≤ -20℃ long term. Avoid repeated freeze-thaw. |
Formulation | Phosphate-buffered solution, pH 7.2. |
Endotoxin | < 1 EU/mg, determined by LAL gel clotting assay |
