Cat. No.：GM-87887MAB
Product：Anti-mouse CD3ε mIgG2a Antibody(145-2C11)
Cat. No.：GM-87887MAB
Product：Anti-mouse CD3ε mIgG2a Antibody(145-2C11)
GM-87887MAB-1mg / 1 mg
GM-87887MAB-5mg / 5 mg
GM-87887MAB-25mg / 25 mg
GM-87887MAB-50mg / 50 mg
GM-87887MAB-100mg / 100mg
Expression System CHO
Aggregation < 5% as determined by SEC-HPLC
Purity > 95% as determined by SDS-PAGE
Endotoxin < 1 EU/mg, determined by LAL gel clotting assay
Sterility 0.2 μm Filtered
Target CD3ε
Clone 145-2C11
Other Names CD3, CD3epsilon, T3e
Source/Isotype Monoclonal mouse IgG2a, kappa
Application /
Description The CD3 ε gene is an important gene in human genome 11 and encodes a CD3 ε protein that is a key component of the T cell receptor (TCR) complex. CD3 complex plays an important role in T cell development, activation and signal transduction.The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women..
Formulation phosphate-buffered solution, pH 7.2
Cat. No.：GM-87887MAB
Product：Anti-mouse CD3ε mIgG2a Antibody(145-2C11)
GM-87887MAB-1mg / 1 mg
GM-87887MAB-5mg / 5 mg
GM-87887MAB-25mg / 25 mg
GM-87887MAB-50mg / 50 mg
GM-87887MAB-100mg / 100mg
Expression System CHO
Aggregation < 5% as determined by SEC-HPLC
Purity > 95% as determined by SDS-PAGE
Endotoxin < 1 EU/mg, determined by LAL gel clotting assay
Sterility 0.2 μm Filtered
Target CD3ε
Clone 145-2C11
Other Names CD3, CD3epsilon, T3e
Source/Isotype Monoclonal mouse IgG2a, kappa
Application /
Description The CD3 ε gene is an important gene in human genome 11 and encodes a CD3 ε protein that is a key component of the T cell receptor (TCR) complex. CD3 complex plays an important role in T cell development, activation and signal transduction.The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women..
Formulation phosphate-buffered solution, pH 7.2
