Cat. No：GM-87928AB
Product：Anti-ACVR2A hIgG1 Antibody(LAE-102)
Cat. No：GM-87928AB
Product：Anti-ACVR2A hIgG1 Antibody(LAE-102)
GM-87928AB-10 10 μg
GM-87928AB-100 100 μg
GM-87928AB-1000 1mg
Species Reactivity | Human |
Clone | LAE-102 |
Source/Isotype | Human IgG1 kappa |
Application | Bioactivity-ELISA |
Target | Detects ACVR2A |
Gene | ACVR2A |
Other Names | ACTRII, ACVR2 |
Gene ID | 92 (Human) |
Background | ACVR2A, a type II receptor that encodes a member of the Transforming growth factor beta (TGF-β) family. It usually forms a complex with type I receptors (such as Alk4/Alk7, also known as ACVR1B/ACVR1C) and activates the intracellular Saring (Smad) signaling pathway, typically phosphorylation and translocation of SMAD2/3, which in turn regulates gene expression. It also participates in signal transduction through non-SMAD pathway. ACVR2A plays an important role in embryonic development and adult tissue homeostasis maintenance in a variety of tissues, affecting epithelial-mesenchymal transition, stem/progenitor cell status, muscle cell differentiation and other processes through Activin/TGF-β-related signaling. |
Storage | Store at 2-8℃ short term (1-2 weeks).Store at ≤ -20℃ long term. Avoid repeated freeze-thaw. |
Formulation | Phosphate-buffered solution, pH 7.2-7.4. |
Endotoxin | < 1 EU/mg, determined by LAL gel clotting assay |
Cat. No：GM-87928AB
Product：Anti-ACVR2A hIgG1 Antibody(LAE-102)
GM-87928AB-10 10 μg
GM-87928AB-100 100 μg
GM-87928AB-1000 1mg
Species Reactivity | Human |
Clone | LAE-102 |
Source/Isotype | Human IgG1 kappa |
Application | Bioactivity-ELISA |
Target | Detects ACVR2A |
Gene | ACVR2A |
Other Names | ACTRII, ACVR2 |
Gene ID | 92 (Human) |
Background | ACVR2A, a type II receptor that encodes a member of the Transforming growth factor beta (TGF-β) family. It usually forms a complex with type I receptors (such as Alk4/Alk7, also known as ACVR1B/ACVR1C) and activates the intracellular Saring (Smad) signaling pathway, typically phosphorylation and translocation of SMAD2/3, which in turn regulates gene expression. It also participates in signal transduction through non-SMAD pathway. ACVR2A plays an important role in embryonic development and adult tissue homeostasis maintenance in a variety of tissues, affecting epithelial-mesenchymal transition, stem/progenitor cell status, muscle cell differentiation and other processes through Activin/TGF-β-related signaling. |
Storage | Store at 2-8℃ short term (1-2 weeks).Store at ≤ -20℃ long term. Avoid repeated freeze-thaw. |
Formulation | Phosphate-buffered solution, pH 7.2-7.4. |
Endotoxin | < 1 EU/mg, determined by LAL gel clotting assay |
