Cat.No：GM-88168MAB
Product ：Anti-Mouse IL13 mIgG2a Antibody (BAK209B11)
Cat.No：GM-88168MAB
Product ：Anti-Mouse IL13 mIgG2a Antibody (BAK209B11)
GM-88168MAB-1mg / 1 mg
GM-88168MAB-5mg / 5 mg
GM-88168MAB-25mg / 5 mg * 5 vials
GM-88168MAB-50mg / 50 mg
GM-88168MAB-100mg / 50 mg * 2 vials
Expression System | CHO |
Aggregation | < 5% as determined by SEC-HPLC |
Purity | > 95% as determined by SDS-PAGE |
Clone | BAK209B11 |
Source/Isotype | Monoclonal Mouse IgG2a kappa |
Application | Bioactivity-ELISA |
Specificity | Detects IL13 |
Gene | IL13 |
Other Names | IL-13, P600 |
Gene ID | 10090 (mouse) |
Background | IL-13 is a cytokine produced by Th2 cells, mast cells, eosinophil granulocyte, ilc2s, etc. . It mainly acts on epithelial tissues such as the airway, skin and intestine, and participates in the regulation of mucosal barrier, mucus secretion, inflammatory cell recruitment and excessive airway remodeling. Sharing a signaling pathway with IL-4(via the IL-4R α/IL-13R α1 complex) , plays a critical role in scenarios such as immune responses, allergies, and parasitic infections. The IL-13 gene is located in a region of a Upstream and downstream shared element, and its expression is regulated by transcription factors such as GATA3 and STAT6 in response to Th2 deflection signals. IL-13 signaling can be modulated by receptor availability, soluble baits, and genetic variants that affect receptor binding or expression. IL-13 activates signaling pathways such as JAK-STAT (especially Stat6) by binding to the complex of receptor IL-4R α with IL-13R α1/2, resulting in altered gene expression and amplification of inflammatory responses. |
Formulation | Phosphate-buffered solution, pH 7.2-7.4. |
Endotoxin | < 1 EU/mg, determined by LAL gel clotting assay |
Cat.No：GM-88168MAB
Product ：Anti-Mouse IL13 mIgG2a Antibody (BAK209B11)
GM-88168MAB-1mg / 1 mg
GM-88168MAB-5mg / 5 mg
GM-88168MAB-25mg / 5 mg * 5 vials
GM-88168MAB-50mg / 50 mg
GM-88168MAB-100mg / 50 mg * 2 vials
Expression System | CHO |
Aggregation | < 5% as determined by SEC-HPLC |
Purity | > 95% as determined by SDS-PAGE |
Clone | BAK209B11 |
Source/Isotype | Monoclonal Mouse IgG2a kappa |
Application | Bioactivity-ELISA |
Specificity | Detects IL13 |
Gene | IL13 |
Other Names | IL-13, P600 |
Gene ID | 10090 (mouse) |
Background | IL-13 is a cytokine produced by Th2 cells, mast cells, eosinophil granulocyte, ilc2s, etc. . It mainly acts on epithelial tissues such as the airway, skin and intestine, and participates in the regulation of mucosal barrier, mucus secretion, inflammatory cell recruitment and excessive airway remodeling. Sharing a signaling pathway with IL-4(via the IL-4R α/IL-13R α1 complex) , plays a critical role in scenarios such as immune responses, allergies, and parasitic infections. The IL-13 gene is located in a region of a Upstream and downstream shared element, and its expression is regulated by transcription factors such as GATA3 and STAT6 in response to Th2 deflection signals. IL-13 signaling can be modulated by receptor availability, soluble baits, and genetic variants that affect receptor binding or expression. IL-13 activates signaling pathways such as JAK-STAT (especially Stat6) by binding to the complex of receptor IL-4R α with IL-13R α1/2, resulting in altered gene expression and amplification of inflammatory responses. |
Formulation | Phosphate-buffered solution, pH 7.2-7.4. |
Endotoxin | < 1 EU/mg, determined by LAL gel clotting assay |
