ALPPL2 (Alkaline Phosphatase, Placental-Like 2), ALPI (Alkaline Phosphatase, Intestinal), ALPL (Tissue-nonspecific alkaline phosphatase, TNSALP), and ALPP (Alkaline Phosphatase, Placental) are isoenzymes belonging to the Alkaline Phosphatase (ALP) superfamily. These genes encode zinc- and magnesium-dependent metalloenzymes that primarily function by hydrolyzing phosphate esters to produce inorganic phosphate, playing crucial roles in various biological processes such as metabolic regulation, bone mineralization, and tumor progression.
Genomeditech provides resources related to ALPPL2 and ALPP, including expression cell lines, proteins, and antibodies, which can be used for in vitro evaluation of ALPPL2 and ALPP-related drug efficacy.