LILRB5 (leukocyte immunoglobulin-like receptor B5) is a protein-coding gene located on human chromosome 19q13.42. LILRB5 is also known as LIR8, CD85C, and LIR-8. The human LILRB5 gene encodes a 64,126 Da protein consisting of 590 amino acids.
LILRB5 protein is widely expressed in the spleen, placenta, and other tissues. Its associated pathways include innate immune system and class I MHC-mediated antigen processing and presentation. LILRB5 is involved in transmembrane signaling receptor activity. LILRB2 is an important paralog of the LILRB5 gene. LILRB5 is associated with hepatic intestinal immunoglobulin-like receptor 2.
