CCR4 (C-C Chemokine Receptor Type 4) is a chemokine receptor belonging to the G protein-coupled receptor (GPCR) family, widely expressed on immune cells such as regulatory T cells (Tregs), Th2 cells, and skin-resident T cells. Its primary ligands, CCL17 (TARC) and CCL22 (MDC), play crucial roles in immune regulation, allergic responses, and the tumor microenvironment.
Genomeditech provides resources related to the CCR4 target, including functional cell lines, expression cell lines, and antibodies, to support activity validation and in vitro efficacy evaluation of CCR4-related drugs.