Cat. No：GM-86015AB
Product：Anti-IL13RA2 hIgG1 Antibody（61H8C1）
Cat. No：GM-86015AB
Product：Anti-IL13RA2 hIgG1 Antibody（61H8C1）
GM-86015AB-10 10 μg
GM-86015AB-100 100 μg
GM-86015AB-1000 1mg
Species Reactivity Human
Clone 61H8C1
Source/Isotype Monoclonal Human IgG1, κ
Application Flow Cytometry
Specificity Detects IL13RA2
Gene IL13RA2
Other Names CD121A, D2S1473, IL-1R-alpha, IL1R, IL1RA, P80
Gene ID 3598(human)
Background Interleukin-13 receptor subunit alpha-2 (IL-13Rα2), also known as CD213A2 (cluster of differentiation 213A2), is a membrane bound protein that in humans is encoded by the IL13RA2 gene. IL-13Rα2 is closely related to IL-13Rα1, a subunit of the interleukin-13 receptor complex. This protein binds IL13 with high affinity, but lacks any significant cytoplasmic domain, and does not appear to function as a signal mediator. It is, however, able to regulate the effects of both IL-13 and IL-4, despite the fact it is unable to bind directly to the latter. It is also reported to play a role in the internalization of IL13. IL-13Rα2 has been found to be over-expressed in a variety of cancers, including pancreatic, ovarian, melanomas, and malignant gliomas.
Storage Store at 2-8℃ short term (1-2 weeks).Store at ≤ -20℃ long term. Avoid repeated freeze-thaw.
Formulation Phosphate-buffered solution, pH 7.2.
Endotoxin < 1 EU/mg, determined by LAL gel clotting assay
Cat. No：GM-86015AB
Product：Anti-IL13RA2 hIgG1 Antibody（61H8C1）
GM-86015AB-10 10 μg
GM-86015AB-100 100 μg
GM-86015AB-1000 1mg
Species Reactivity Human
Clone 61H8C1
Source/Isotype Monoclonal Human IgG1, κ
Application Flow Cytometry
Specificity Detects IL13RA2
Gene IL13RA2
Other Names CD121A, D2S1473, IL-1R-alpha, IL1R, IL1RA, P80
Gene ID 3598(human)
Background Interleukin-13 receptor subunit alpha-2 (IL-13Rα2), also known as CD213A2 (cluster of differentiation 213A2), is a membrane bound protein that in humans is encoded by the IL13RA2 gene. IL-13Rα2 is closely related to IL-13Rα1, a subunit of the interleukin-13 receptor complex. This protein binds IL13 with high affinity, but lacks any significant cytoplasmic domain, and does not appear to function as a signal mediator. It is, however, able to regulate the effects of both IL-13 and IL-4, despite the fact it is unable to bind directly to the latter. It is also reported to play a role in the internalization of IL13. IL-13Rα2 has been found to be over-expressed in a variety of cancers, including pancreatic, ovarian, melanomas, and malignant gliomas.
Storage Store at 2-8℃ short term (1-2 weeks).Store at ≤ -20℃ long term. Avoid repeated freeze-thaw.
Formulation Phosphate-buffered solution, pH 7.2.
Endotoxin < 1 EU/mg, determined by LAL gel clotting assay
