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Cytokine
Background


Cytokines (CK) are low molecular weight soluble proteins induced by immune agents, mitogens, or other stimulants, produced by various cells with functions including regulating innate and adaptive immunity, hematopoiesis, cell growth, APSC pluripotent cells, tissue repair, etc. Cytokines can be categorized into interleukins, interferons, tumor necrosis factor superfamily, colony-stimulating factors, chemokines, growth factors, etc. These multifunctional cytokines exert their effects through paracrine, autocrine, or endocrine pathways, exhibiting pleiotropy, redundancy, antagonism, synergy, among other physiological characteristics, forming a complex cytokine regulatory network involved in various important physiological functions in the human body.

Cytokines play crucial roles in the development, differentiation, immune responses, and immune regulation processes of immune cells. However, they can also act as a double-edged sword and under certain conditions participate in the onset of various diseases. For example, during immune responses, immune cells secrete large amounts of cytokines, which in turn stimulate immune cells. If this positive feedback regulation fails, it can lead to a "cytokine storm." "Cytokine storms" can occur in various diseases such as acute respiratory distress syndrome, SARS (severe acute respiratory syndrome), and influenza, among others.


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Products
Target Cat. No. Product
TGF-β
GM-82350AB
Anti-ACVR2B hIgG1 Antibody(Fab-17G05)
TGF-β
GM-81622AB
Anti-ITGB6 hIgG1 Antibody(SGN-B6A)
TGF-β
GM-53193AB
Anti-αvβ6 hIgG1 Antibody(m15H3)
TGF-β
GM-51148AB
Anti-ACVR2B hIgG1 Antibody(Bimagrumab)
TGF-β
GM-30474AB
Anti-GARP-TGF-β1 hIgG4 Antibody(ARGX-115)
TGF-β
GM-26831AB
Anti-TGFB1 hIgG4 Antibody(SRK-181)
TGF-β
GM-49298AB
Anti-αv hIgG2 Antibody(Abituzumab)
TGF-β
GM-86367MAB
Anti-H_ACVR2B hIgG1 Reference Antibody(Bimbio)
TGF-β
GM-87700AB
Anti-ACVR2B mIgG2a Antibody(Bimagrumab)
VEGF
GM-51978AB
Anti-VEGF hIgG1 Antibody(Bevacizumab)
VEGF
GM-87758MAB
Anti-VEGF hIgG1 Reference Antibody (Bevbio)
VEGF
GM-87757MAB
Anti-VEGFxPD1 hIgG1 Reference Antibody
GDF15
GM-71274AB
Anti-H_GDF15 hIgG4 Antibody(CTL-002)
GDF15
GM-87500MAB
Anti-GDF15 hIgG1 Reference Antibody(Ponsbio)
GDF15
GM-71276AB
Anti-H_GFRAL hIgG4 Antibody(QUEL-0301)
IL-12
GM-46333AB
Anti-IL-12/23(p40) hIgG1 antibody(Ustekinumab)
IL-7
GM-52274AB
Anti-IL7Ra hIgG1 Antibody(4A10)
IL-11
GM-57288AB
Anti-IL-11 hIgG4 Antibody(Hu16E12)
IL-11RA
GM-57287AB
Anti-IL-11RA hIgG1 Antibody(58B10-9C3-4E5)
IL-4
GM-53165AB
Anti-IL4R hIgG4 Antibody(Dupilumab)
IL-4
GM-46268AB
Anti-IL-4R hIgG1 Antibody(12B5)
IL-4R
GM-87496MAB
Anti-IL4R hIgG4 Reference Antibody (Dupbio)
CTGF(CCN2):aVb3
GM-51125AB
Anti-ITGB3 hIgG1 Antibody(etaracizumab)
CTGF(CCN2):aVb3
GM-51031AB
Anti-CTGF hIgG1 Antibody(Pamrevlumab)
IL-31
GM-50883AB
Anti-IL31 hIgG1 Antibody(mAb33)
IL-31
GM-50874AB
Anti-OSMR hIgG4 Antibody(Vixarelimab)
IL-33
GM-31628AB
Anti-IL33 hIgG4 Antibody(Itepekimab)
IL-2
GM-52319AB
Anti-CD122 hIgG1 Antibody(HuABC-2)
IL-5
GM-52408AB
Anti-IL5 hIgG4 Antibody(Reslizumab)
IL-5
GM-46851AB
Anti-IL-5R hIgG1 Antibody(Benralizumab)
IL-2
GM-52334AB
Anti-CD132(IL2RG) hIgG4 Antibody(REGN7257)
IL-2
GM-52329AB
Anti-CD25 hIgG1 Antibody(Basiliximab)
IL-1
GM-51990AB
Anti-IL1R1 hIgG1 Antibody(AMG 108)
IL-1β
GM-51764AB
Anti-IL-1β hIgG1 Antibody(Canakinumab)
IL-31
GM-50880AB
Anti-IL31RA hIgG1 Antibody(NA633)
IL-31
GM-50871AB
Anti-IL31RA hIgG2 Antibody(Nemolizumab)
IL-17
GM-27267AB
Anti-IL-17A hIgG1 Antibody(Secukinumab)
IL-17
GM-87353MAB
Anti-IL17A hIgG1 Reference Antibody (Secubio)
PRL-PRLR
GM-27198AB
Anti-PRLR hIgG1 Antibody(Mat3)
IL-22
GM-46509AB
Anti-H_IL-22 hIgG1 Antibody(Fezakinumab)
IL-22
GM-46382AB
Anti-H_IL-22R1 hIgG1 Antibody(ARGX-112)
NPR1
GM-87696AB
Anti-NPR1 hIgG1 Antibody(XX-16)
NPR1
GM-87697AB
Anti-NPR1 hIgG4 Antibody(REGN-5381)
EphA2
GM-87695AB
Anti-EphA2 hIgG1 Antibody(MEDI-547)
PRLR
GM-87347MAB
Anti-PRLR hIgG1 Reference Antibody(Mat3)
IGF-1R
GM-87441AB
Anti-IGF-1R hIgG1 Antibody(teprotumumab)
IL-33
GM-87354MAB
Anti-IL33 hIgG4 ReferenceAntibody (Itepbio)
RANKL
GM-77688AB
Anti-H_RANKL hIgG2 Antibody(Denosumab)
IL-23R
GM-87786AB
Anti-IL-23R hIgG1 Antibody(5D4)
Product Center > Antibodies > Biosimilar Antibodies
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Cytokine
Products
Target Cat. No. Product
TGF-β
GM-82350AB
Anti-ACVR2B hIgG1 Antibody(Fab-17G05)
TGF-β
GM-81622AB
Anti-ITGB6 hIgG1 Antibody(SGN-B6A)
TGF-β
GM-53193AB
Anti-αvβ6 hIgG1 Antibody(m15H3)
TGF-β
GM-51148AB
Anti-ACVR2B hIgG1 Antibody(Bimagrumab)
TGF-β
GM-30474AB
Anti-GARP-TGF-β1 hIgG4 Antibody(ARGX-115)
TGF-β
GM-26831AB
Anti-TGFB1 hIgG4 Antibody(SRK-181)
TGF-β
GM-49298AB
Anti-αv hIgG2 Antibody(Abituzumab)
TGF-β
GM-86367MAB
Anti-H_ACVR2B hIgG1 Reference Antibody(Bimbio)
TGF-β
GM-87700AB
Anti-ACVR2B mIgG2a Antibody(Bimagrumab)
VEGF
GM-51978AB
Anti-VEGF hIgG1 Antibody(Bevacizumab)
VEGF
GM-87758MAB
Anti-VEGF hIgG1 Reference Antibody (Bevbio)
VEGF
GM-87757MAB
Anti-VEGFxPD1 hIgG1 Reference Antibody
GDF15
GM-71274AB
Anti-H_GDF15 hIgG4 Antibody(CTL-002)
GDF15
GM-87500MAB
Anti-GDF15 hIgG1 Reference Antibody(Ponsbio)
GDF15
GM-71276AB
Anti-H_GFRAL hIgG4 Antibody(QUEL-0301)
IL-12
GM-46333AB
Anti-IL-12/23(p40) hIgG1 antibody(Ustekinumab)
IL-7
GM-52274AB
Anti-IL7Ra hIgG1 Antibody(4A10)
IL-11
GM-57288AB
Anti-IL-11 hIgG4 Antibody(Hu16E12)
IL-11RA
GM-57287AB
Anti-IL-11RA hIgG1 Antibody(58B10-9C3-4E5)
IL-4
GM-53165AB
Anti-IL4R hIgG4 Antibody(Dupilumab)
IL-4
GM-46268AB
Anti-IL-4R hIgG1 Antibody(12B5)
IL-4R
GM-87496MAB
Anti-IL4R hIgG4 Reference Antibody (Dupbio)
CTGF(CCN2):aVb3
GM-51125AB
Anti-ITGB3 hIgG1 Antibody(etaracizumab)
CTGF(CCN2):aVb3
GM-51031AB
Anti-CTGF hIgG1 Antibody(Pamrevlumab)
IL-31
GM-50883AB
Anti-IL31 hIgG1 Antibody(mAb33)
IL-31
GM-50874AB
Anti-OSMR hIgG4 Antibody(Vixarelimab)
IL-33
GM-31628AB
Anti-IL33 hIgG4 Antibody(Itepekimab)
IL-2
GM-52319AB
Anti-CD122 hIgG1 Antibody(HuABC-2)
IL-5
GM-52408AB
Anti-IL5 hIgG4 Antibody(Reslizumab)
IL-5
GM-46851AB
Anti-IL-5R hIgG1 Antibody(Benralizumab)
IL-2
GM-52334AB
Anti-CD132(IL2RG) hIgG4 Antibody(REGN7257)
IL-2
GM-52329AB
Anti-CD25 hIgG1 Antibody(Basiliximab)
IL-1
GM-51990AB
Anti-IL1R1 hIgG1 Antibody(AMG 108)
IL-1β
GM-51764AB
Anti-IL-1β hIgG1 Antibody(Canakinumab)
IL-31
GM-50880AB
Anti-IL31RA hIgG1 Antibody(NA633)
IL-31
GM-50871AB
Anti-IL31RA hIgG2 Antibody(Nemolizumab)
IL-17
GM-27267AB
Anti-IL-17A hIgG1 Antibody(Secukinumab)
IL-17
GM-87353MAB
Anti-IL17A hIgG1 Reference Antibody (Secubio)
PRL-PRLR
GM-27198AB
Anti-PRLR hIgG1 Antibody(Mat3)
IL-22
GM-46509AB
Anti-H_IL-22 hIgG1 Antibody(Fezakinumab)
IL-22
GM-46382AB
Anti-H_IL-22R1 hIgG1 Antibody(ARGX-112)
NPR1
GM-87696AB
Anti-NPR1 hIgG1 Antibody(XX-16)
NPR1
GM-87697AB
Anti-NPR1 hIgG4 Antibody(REGN-5381)
EphA2
GM-87695AB
Anti-EphA2 hIgG1 Antibody(MEDI-547)
PRLR
GM-87347MAB
Anti-PRLR hIgG1 Reference Antibody(Mat3)
IGF-1R
GM-87441AB
Anti-IGF-1R hIgG1 Antibody(teprotumumab)
IL-33
GM-87354MAB
Anti-IL33 hIgG4 ReferenceAntibody (Itepbio)
RANKL
GM-77688AB
Anti-H_RANKL hIgG2 Antibody(Denosumab)
IL-23R
GM-87786AB
Anti-IL-23R hIgG1 Antibody(5D4)
Background


Cytokines (CK) are low molecular weight soluble proteins induced by immune agents, mitogens, or other stimulants, produced by various cells with functions including regulating innate and adaptive immunity, hematopoiesis, cell growth, APSC pluripotent cells, tissue repair, etc. Cytokines can be categorized into interleukins, interferons, tumor necrosis factor superfamily, colony-stimulating factors, chemokines, growth factors, etc. These multifunctional cytokines exert their effects through paracrine, autocrine, or endocrine pathways, exhibiting pleiotropy, redundancy, antagonism, synergy, among other physiological characteristics, forming a complex cytokine regulatory network involved in various important physiological functions in the human body.

Cytokines play crucial roles in the development, differentiation, immune responses, and immune regulation processes of immune cells. However, they can also act as a double-edged sword and under certain conditions participate in the onset of various diseases. For example, during immune responses, immune cells secrete large amounts of cytokines, which in turn stimulate immune cells. If this positive feedback regulation fails, it can lead to a "cytokine storm." "Cytokine storms" can occur in various diseases such as acute respiratory distress syndrome, SARS (severe acute respiratory syndrome), and influenza, among others.


细胞因子-2.png

Catologe
Anti-ACVR2B hIgG1 Antibody(Fab-17G05) Anti-ITGB6 hIgG1 Antibody(SGN-B6A) Anti-αvβ6 hIgG1 Antibody(m15H3) Anti-αv hIgG2 Antibody(Abituzumab) Anti-H_ACVR2B hIgG1 Reference Antibody(Bimbio) Anti-VEGF hIgG1 Antibody(Bevacizumab) Anti-H_GDF15 hIgG4 Antibody(CTL-002) Anti-H_GFRAL hIgG4 Antibody(QUEL-0301) Anti-IL1R1 hIgG1 Antibody(AMG 108) Anti-IL31RA hIgG2 Antibody(Nemolizumab) Anti-PRLR hIgG1 Antibody(Mat3) Anti-ITGB3 hIgG1 Antibody(etaracizumab) Anti-CTGF hIgG1 Antibody(Pamrevlumab) Anti-IL31 hIgG1 Antibody(mAb33) Anti-TGFB1 hIgG4 Antibody(SRK-181) Anti-IL-5R hIgG1 Antibody(Benralizumab) Anti-H_IL-22 hIgG1 Antibody(Fezakinumab) Anti-H_IL-22R1 hIgG1 Antibody(ARGX-112) Anti-ACVR2B hIgG1 Antibody(Bimagrumab) Anti-GARP-TGF-β1 hIgG4 Antibody(ARGX-115) Anti-IL-12/23(p40) hIgG1 antibody(Ustekinumab) Anti-IL7Ra hIgG1 Antibody(4A10) Anti-IL-11 hIgG4 Antibody(Hu16E12) Anti-IL4R hIgG4 Antibody(Dupilumab) Anti-IL-4R hIgG1 Antibody(12B5) Anti-OSMR hIgG4 Antibody(Vixarelimab) Anti-IL33 hIgG4 Antibody(Itepekimab) Anti-CD122 hIgG1 Antibody(HuABC-2) Anti-IL5 hIgG4 Antibody(Reslizumab) Anti-CD132(IL2RG) hIgG4 Antibody(REGN7257) Anti-CD25 hIgG1 Antibody(Basiliximab) Anti-IL-1β hIgG1 Antibody(Canakinumab) Anti-IL31RA hIgG1 Antibody(NA633) Anti-IL-17A hIgG1 Antibody(Secukinumab) Anti-H_IL-22R1 hIgG1 Antibody(ARGX-112) Anti-GDF15 hIgG1 Reference Antibody(Ponsbio) Anti-ACVR2B mIgG2a Antibody(Bimagrumab) Anti-IL17A hIgG1 Reference Antibody (Secubio) Anti-VEGF hIgG1 Reference Antibody (Bevbio) Anti-IL4R hIgG4 Reference Antibody (Dupbio) Anti-H_ITGB6 hIgG1 Reference Antibody (h2A2) Anti-IL-11RA hIgG1 Antibody(58B10-9C3-4E5) Anti-IL33 hIgG4 ReferenceAntibody (Itepbio) Anti-NPR1 hIgG1 Antibody(XX-16) Anti-NPR1 hIgG4 Antibody(REGN-5381) Anti-EphA2 hIgG1 Antibody(MEDI-547) Anti-PRLR hIgG1 Reference Antibody (Mat3) Anti-IGF-1R hIgG1 Antibody(teprotumumab) Anti-H_RANKL hIgG2 Antibody(Denosumab) Anti-IL-23R hIgG1 Antibody(5D4) Anti-VEGFxPD1 hIgG1 Reference Antibody (Ivobio)
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