Cat.No：GM-81150AB
Product ：Anti-ITGB6-MMAE ADC(Dar4)[SGN-B6A]
Cat.No：GM-81150AB
Product ：Anti-ITGB6-MMAE ADC(Dar4)[SGN-B6A]
GM-81151AB-100 100μg
GM-81151AB-1mg 1mg
Expression System CHO
Aggregation < 5% as determined by SEC-HPLC
Purity >95% as determined by SDS-PAGE
Drug-to-Antibody Ratio (DAR) 4.0
Endotoxin <1 EU/mg, determined by LAL gel clotting assay
Sterility 0.22 μm Filtered
Target ITGB6
Clone SGN-B6A
Alternative Names AI1H; ITGB6
Source/lsotype Monoclonal Human IgG1（KDEL), Kappa
Application ELISA, FACS, Cell-based Assay, Animal Model
Description SGN-B6A is an ITGB6-directed vedotin ADC with a monomethyl auristatin E (MMAE) payload. SGN-B6A elicits antitumor activity via MMAE-mediated cytotoxicity, bystander effect, and immunogenic cell death.
Formulation 20 mM Histidine, pH 6.0
Storage temp. Store at +4°C short term. Store at -80°C for 36 months, avoiding freeze/thaw cycles.
Cat.No：GM-81150AB
Product ：Anti-ITGB6-MMAE ADC(Dar4)[SGN-B6A]
GM-81151AB-100 100μg
GM-81151AB-1mg 1mg
Expression System CHO
Aggregation < 5% as determined by SEC-HPLC
Purity >95% as determined by SDS-PAGE
Drug-to-Antibody Ratio (DAR) 4.0
Endotoxin <1 EU/mg, determined by LAL gel clotting assay
Sterility 0.22 μm Filtered
Target ITGB6
Clone SGN-B6A
Alternative Names AI1H; ITGB6
Source/lsotype Monoclonal Human IgG1（KDEL), Kappa
Application ELISA, FACS, Cell-based Assay, Animal Model
Description SGN-B6A is an ITGB6-directed vedotin ADC with a monomethyl auristatin E (MMAE) payload. SGN-B6A elicits antitumor activity via MMAE-mediated cytotoxicity, bystander effect, and immunogenic cell death.
Formulation 20 mM Histidine, pH 6.0
Storage temp. Store at +4°C short term. Store at -80°C for 36 months, avoiding freeze/thaw cycles.
