Cat. No：GM-51390AB
Product：Anti-INSR hIgG1 Antibody(XPA.15.247.2.018)
Cat. No：GM-51390AB
Product：Anti-INSR hIgG1 Antibody(XPA.15.247.2.018)
GM-51390AB-10 10 μg
GM-51390AB-100 100 μg
GM-51390AB-1000 1mg
Species Reactivity Human
Clone XPA.15.247.2.018
Source/Isotype Monoclonal human IgG1/κ
Application Block assay
Specificity Detects human INSR.
Gene INSR
Other Names HHF5; CD220
Gene ID 3643
Background This gene encodes a member of the receptor tyrosine kinase family of proteins. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form a heterotetrameric receptor. Binding of insulin or other ligands to this receptor activates the insulin signaling pathway, which regulates glucose uptake and release, as well as the synthesis and storage of carbohydrates, lipids and protein. Mutations in this gene underlie the inherited severe insulin resistance syndromes including type A insulin resistance syndrome, Donohue syndrome and Rabson-Mendenhall syndrome.
Storage Store at +4℃ short term (1-2 weeks). Store at -20℃ long term
Formulation Phosphate-buffered solution, pH 7.2.
Endotoxin < 1 EU/mg, determined by LAL gel clotting assay
Cat. No：GM-51390AB
Product：Anti-INSR hIgG1 Antibody(XPA.15.247.2.018)
GM-51390AB-10 10 μg
GM-51390AB-100 100 μg
GM-51390AB-1000 1mg
Species Reactivity Human
Clone XPA.15.247.2.018
Source/Isotype Monoclonal human IgG1/κ
Application Block assay
Specificity Detects human INSR.
Gene INSR
Other Names HHF5; CD220
Gene ID 3643
Background This gene encodes a member of the receptor tyrosine kinase family of proteins. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form a heterotetrameric receptor. Binding of insulin or other ligands to this receptor activates the insulin signaling pathway, which regulates glucose uptake and release, as well as the synthesis and storage of carbohydrates, lipids and protein. Mutations in this gene underlie the inherited severe insulin resistance syndromes including type A insulin resistance syndrome, Donohue syndrome and Rabson-Mendenhall syndrome.
Storage Store at +4℃ short term (1-2 weeks). Store at -20℃ long term
Formulation Phosphate-buffered solution, pH 7.2.
Endotoxin < 1 EU/mg, determined by LAL gel clotting assay
