Cat. No：GM-47423AB
Product ：Anti-Cynomolgus_CCR8 hIgG1 Antibody（TPP-21360）
Cat. No：GM-47423AB
Product ：Anti-Cynomolgus_CCR8 hIgG1 Antibody（TPP-21360）
GM-47423AB-10 10 μg
GM-47423AB-100 100 μg
GM-47423AB-1000 1mg
Species Reactivity Cynomolgus
Clone TPP-21360
Source/Isotype Monoclonal Human IgG1 /κ
Application Flow Cytometry
Specificity Detects CCR8
Gene CCR8
Other Names CY6; TER1; CCR-8; CKRL1; CDw1 98; CMKBR8; GPRCY6; CMKBRL2;CC-CKR-8
Gene ID 102132857
Background CCR8, also known as ChemR1, TER1, and CKR-L1, belongs to the beta chemokine receptor family. It is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. CCR8 is expressed on some subsets of T cells, monocytes, macrophages, eosinophils, thymocytes, Langerhans cells, neurons, and vascular smooth muscle cells. Binding with its ligand CCL1, CCR8 plays a role in the regulation of monocyte chemotaxis and thymic cell apoptosis. It has been reported that CCR8 is also a receptor for CCL18. CCR8 is also believed to be an alternative coreceptor to CD4 for HIV-1 infection.
Storage Store at 2-8℃ short term (1-2 weeks).Store at ≤ -20℃ long term. Avoid repeated freeze-thaw.
Formulation Phosphate-buffered solution, pH 7.2.
Endotoxin < 1 EU/mg, determined by LAL gel clotting assay
Cat. No：GM-47423AB
Product ：Anti-Cynomolgus_CCR8 hIgG1 Antibody（TPP-21360）
GM-47423AB-10 10 μg
GM-47423AB-100 100 μg
GM-47423AB-1000 1mg
Species Reactivity Cynomolgus
Clone TPP-21360
Source/Isotype Monoclonal Human IgG1 /κ
Application Flow Cytometry
Specificity Detects CCR8
Gene CCR8
Other Names CY6; TER1; CCR-8; CKRL1; CDw1 98; CMKBR8; GPRCY6; CMKBRL2;CC-CKR-8
Gene ID 102132857
Background CCR8, also known as ChemR1, TER1, and CKR-L1, belongs to the beta chemokine receptor family. It is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. CCR8 is expressed on some subsets of T cells, monocytes, macrophages, eosinophils, thymocytes, Langerhans cells, neurons, and vascular smooth muscle cells. Binding with its ligand CCL1, CCR8 plays a role in the regulation of monocyte chemotaxis and thymic cell apoptosis. It has been reported that CCR8 is also a receptor for CCL18. CCR8 is also believed to be an alternative coreceptor to CD4 for HIV-1 infection.
Storage Store at 2-8℃ short term (1-2 weeks).Store at ≤ -20℃ long term. Avoid repeated freeze-thaw.
Formulation Phosphate-buffered solution, pH 7.2.
Endotoxin < 1 EU/mg, determined by LAL gel clotting assay
