Cat.No：GM-53822AB
Product：Anti-H_CCR8 hIgG1 Antibody(Defucosylated,BMS-986340)
Cat.No：GM-53822AB
Product：Anti-H_CCR8 hIgG1 Antibody(Defucosylated,BMS-986340)
GM-53822AB-100 100 μg
GM-53822AB-1000 1 mg
Species Reactivity Human
Clone Defucosylated,BMS-986340
Source/Isotype Monoclonal Human IgG1
Application Flow Cytometry; Bioassay
Specificity Detects CCR8
Gene CCR8
Other Names CY6，TER1，CCR-8，CKRL1，CDw1 98，CMKBR8，GPRCY6，CMKBRL2，CC-CKR-8
Gene ID 1237
Background CCR8, also known as ChemR1, TER1, and CKR-L1, belongs to the beta chemokine receptor family. It is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. CCR8 is expressed on some subsets of T cells, monocytes, macrophages, eosinophils, thymocytes, Langerhans cells, neurons, and vascular smooth muscle cells. Binding with its ligand CCL1, CCR8 plays a role in the regulation of monocyte chemotaxis and thymic cell apoptosis. It has been reported that CCR8 is also a receptor for CCL18. CCR8 is also believed to be an alternative coreceptor to CD4 for HIV-1 infection.
Storage Store at 2-8℃ short term (1-2 weeks).Store at ≤ -20℃ long term. Avoid repeated freeze-thaw.
Formulation Phosphate-buffered solution, pH 7.2.
Endotoxin < 1 EU/mg, determined by LAL gel clotting assay
Cat.No：GM-53822AB
Product：Anti-H_CCR8 hIgG1 Antibody(Defucosylated,BMS-986340)
GM-53822AB-100 100 μg
GM-53822AB-1000 1 mg
Species Reactivity Human
Clone Defucosylated,BMS-986340
Source/Isotype Monoclonal Human IgG1
Application Flow Cytometry; Bioassay
Specificity Detects CCR8
Gene CCR8
Other Names CY6，TER1，CCR-8，CKRL1，CDw1 98，CMKBR8，GPRCY6，CMKBRL2，CC-CKR-8
Gene ID 1237
Background CCR8, also known as ChemR1, TER1, and CKR-L1, belongs to the beta chemokine receptor family. It is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. CCR8 is expressed on some subsets of T cells, monocytes, macrophages, eosinophils, thymocytes, Langerhans cells, neurons, and vascular smooth muscle cells. Binding with its ligand CCL1, CCR8 plays a role in the regulation of monocyte chemotaxis and thymic cell apoptosis. It has been reported that CCR8 is also a receptor for CCL18. CCR8 is also believed to be an alternative coreceptor to CD4 for HIV-1 infection.
Storage Store at 2-8℃ short term (1-2 weeks).Store at ≤ -20℃ long term. Avoid repeated freeze-thaw.
Formulation Phosphate-buffered solution, pH 7.2.
Endotoxin < 1 EU/mg, determined by LAL gel clotting assay
