Anti-H_CCR8 hIgG1 Reference Antibody, Defucosylation (BMS-986340)
Cat. No.
GM-53822MAB
Size
Quote
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Product info
Cat. No. & Size
Description️
Data
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Product info

Cat.No:GM-53822MAB

Product:Anti-H_CCR8 hIgG1 Reference Antibody, Defucosylation (BMS-986340)




Cat. No. & Size

GM-53822MAB-1mg / 1 mg

GM-53822MAB-5mg / 5 mg

GM-53822MAB-25mg / 5 mg * 5 vials

GM-53822MAB-50mg / 50 mg

GM-53822MAB-100mg / 50 mg * 2 vials



Description️

Expression System

CHO

Aggregation

< 5% as determined by SEC-HPLC

Purity

> 95% as determined by SDS-PAGE

Species Reactivity

Human

Clone

Defucosylated,BMS-986340

Source/Isotype

Monoclonal Human IgG1

Application

Flow Cytometry; Bioassay; Bioactivity-ELISA

Specificity

Detects CCR8

Gene

CCR8

Other Names

CY6; TER1; CCR-8; CKRL1; CDw1 98; CMKBR8; GPRCY6; CMKBRL2;


CC-CKR-8

Gene ID

1237

Background

CCR8, also known as ChemR1, TER1, and CKR-L1, belongs to the beta chemokine receptor family. It is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. CCR8 is expressed on some subsets of T cells, monocytes, macrophages, eosinophils, thymocytes, Langerhans cells, neurons, and vascular smooth muscle cells. Binding with its ligand CCL1, CCR8 plays a role in the regulation of monocyte chemotaxis and thymic cell apoptosis. It has been reported that CCR8 is also a receptor for CCL18. CCR8 is also believed to be an alternative coreceptor to CD4 for HIV-1 infection.

Storage

Store at 2-8°C short term (1-2 weeks). Store at ≤ -20°C long term.Avoid repeated freeze-thaw.

Formulation

Phosphate-buffered solution, pH 7.2-7.4.

Endotoxin

< 1 EU/mg, determined by LAL gel clotting assay



Data

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For laboratory research use only. Direct human use, including taking orally and injection and clinical use are forbidden.
Anti-H_CCR8 hIgG1 Reference Antibody, Defucosylation (BMS-986340)
Cat. No.
GM-53822MAB
Size
Quote
Related products
Product info
Cat. No. & Size
Description️
Data
Related products
Product info

Cat.No:GM-53822MAB

Product:Anti-H_CCR8 hIgG1 Reference Antibody, Defucosylation (BMS-986340)




Cat.No:GM-53822MAB

Product:Anti-H_CCR8 hIgG1 Reference Antibody, Defucosylation (BMS-986340)




Cat. No. & Size

GM-53822MAB-1mg / 1 mg

GM-53822MAB-5mg / 5 mg

GM-53822MAB-25mg / 5 mg * 5 vials

GM-53822MAB-50mg / 50 mg

GM-53822MAB-100mg / 50 mg * 2 vials



GM-53822MAB-1mg / 1 mg

GM-53822MAB-5mg / 5 mg

GM-53822MAB-25mg / 5 mg * 5 vials

GM-53822MAB-50mg / 50 mg

GM-53822MAB-100mg / 50 mg * 2 vials



Description️

Expression System

CHO

Aggregation

< 5% as determined by SEC-HPLC

Purity

> 95% as determined by SDS-PAGE

Species Reactivity

Human

Clone

Defucosylated,BMS-986340

Source/Isotype

Monoclonal Human IgG1

Application

Flow Cytometry; Bioassay; Bioactivity-ELISA

Specificity

Detects CCR8

Gene

CCR8

Other Names

CY6; TER1; CCR-8; CKRL1; CDw1 98; CMKBR8; GPRCY6; CMKBRL2;


CC-CKR-8

Gene ID

1237

Background

CCR8, also known as ChemR1, TER1, and CKR-L1, belongs to the beta chemokine receptor family. It is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. CCR8 is expressed on some subsets of T cells, monocytes, macrophages, eosinophils, thymocytes, Langerhans cells, neurons, and vascular smooth muscle cells. Binding with its ligand CCL1, CCR8 plays a role in the regulation of monocyte chemotaxis and thymic cell apoptosis. It has been reported that CCR8 is also a receptor for CCL18. CCR8 is also believed to be an alternative coreceptor to CD4 for HIV-1 infection.

Storage

Store at 2-8°C short term (1-2 weeks). Store at ≤ -20°C long term.Avoid repeated freeze-thaw.

Formulation

Phosphate-buffered solution, pH 7.2-7.4.

Endotoxin

< 1 EU/mg, determined by LAL gel clotting assay



Expression System

CHO

Aggregation

< 5% as determined by SEC-HPLC

Purity

> 95% as determined by SDS-PAGE

Species Reactivity

Human

Clone

Defucosylated,BMS-986340

Source/Isotype

Monoclonal Human IgG1

Application

Flow Cytometry; Bioassay; Bioactivity-ELISA

Specificity

Detects CCR8

Gene

CCR8

Other Names

CY6; TER1; CCR-8; CKRL1; CDw1 98; CMKBR8; GPRCY6; CMKBRL2;


CC-CKR-8

Gene ID

1237

Background

CCR8, also known as ChemR1, TER1, and CKR-L1, belongs to the beta chemokine receptor family. It is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. CCR8 is expressed on some subsets of T cells, monocytes, macrophages, eosinophils, thymocytes, Langerhans cells, neurons, and vascular smooth muscle cells. Binding with its ligand CCL1, CCR8 plays a role in the regulation of monocyte chemotaxis and thymic cell apoptosis. It has been reported that CCR8 is also a receptor for CCL18. CCR8 is also believed to be an alternative coreceptor to CD4 for HIV-1 infection.

Storage

Store at 2-8°C short term (1-2 weeks). Store at ≤ -20°C long term.Avoid repeated freeze-thaw.

Formulation

Phosphate-buffered solution, pH 7.2-7.4.

Endotoxin

< 1 EU/mg, determined by LAL gel clotting assay



Data

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