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Current position:Product Center > Antibodies > Biosimilar Antibodies > Anti-OX40L hIgG1 Reference Antibody (Oxebio)
Anti-OX40L hIgG1 Reference Antibody (Oxebio)
Product Info

Cat. No:GM-87694MAB

Product:Anti-OX40L hIgG1 Reference Antibody (Oxebio)

Cat.No.&Size

GM-87694MAB-1mg / 1 mg

GM-87694MAB-5mg / 5 mg

GM-87694MAB-25mg / 25 mg

GM-87694MAB-50mg / 50mg

GM-87694MAB-100mg / 100mg


Description

Expression System        CHO

Aggregation                  < 5% as determined by SEC-HPLC

Purity                             > 95% as determined by SDS-PAGE

Endotoxin                      < 1 EU/mg, determined by LAL gel clotting assay

Sterility                           0.2 μm Filtered

Target                             OX40L

Clone                              Oxelumab

Alternative Names        CD134L, CD252, GP34, OX-40L, OX4OL, TNLG2B, TXGP1

Source/Isotype              Human IgG1(K214R/D356E/L358M,Delta K447), Kappa

Application                     /

Description                    OX40L, is not expressed on resting antigen presenting cells, but is following their activation. Expression of OX40 is dependent on full activation of the T cell; without CD28, expression of OX40 is delayed and of fourfold lower levels. OX40L binds to OX40 receptors on T-cells, preventing them from dying and subsequently increasing cytokine production. OX40 has a critical role in the maintenance of an immune response beyond the first few days and onwards to a memory response due to its ability to enhance survival. OX40 also plays a crucial role in both Th1 and Th2 mediated reactions in vivo.

Formulation                   Phosphate-buffered solution, pH 7.4.


Data

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Current position:Product Center > -- > Anti-OX40L hIgG1 Reference Antibody (Oxebio)
classify
Anti-OX40L hIgG1 Reference Antibody (Oxebio)
Product Info

Cat. No:GM-87694MAB

Product:Anti-OX40L hIgG1 Reference Antibody (Oxebio)

Cat.No.&Size

GM-87694MAB-1mg / 1 mg

GM-87694MAB-5mg / 5 mg

GM-87694MAB-25mg / 25 mg

GM-87694MAB-50mg / 50mg

GM-87694MAB-100mg / 100mg


Description

Expression System        CHO

Aggregation                  < 5% as determined by SEC-HPLC

Purity                             > 95% as determined by SDS-PAGE

Endotoxin                      < 1 EU/mg, determined by LAL gel clotting assay

Sterility                           0.2 μm Filtered

Target                             OX40L

Clone                              Oxelumab

Alternative Names        CD134L, CD252, GP34, OX-40L, OX4OL, TNLG2B, TXGP1

Source/Isotype              Human IgG1(K214R/D356E/L358M,Delta K447), Kappa

Application                     /

Description                    OX40L, is not expressed on resting antigen presenting cells, but is following their activation. Expression of OX40 is dependent on full activation of the T cell; without CD28, expression of OX40 is delayed and of fourfold lower levels. OX40L binds to OX40 receptors on T-cells, preventing them from dying and subsequently increasing cytokine production. OX40 has a critical role in the maintenance of an immune response beyond the first few days and onwards to a memory response due to its ability to enhance survival. OX40 also plays a crucial role in both Th1 and Th2 mediated reactions in vivo.

Formulation                   Phosphate-buffered solution, pH 7.4.


Data

image.png


image.png

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