Cat. No：GM-87688AB
Product：Anti-GPNMB hlgG2 Antibody(glembatumumab)
Cat. No：GM-87688AB
Product：Anti-GPNMB hlgG2 Antibody(glembatumumab)
GM-87688AB-10 10 μg
GM-87688AB-100 100 μg
GM-87688AB-1000 1mg
Species Reactivity Human;
Clone glembatumumab
Source/Isotype Monoclonal human IgG2, κ
Application Bioactivity-ELISA
Specificity Detects GPNMB
Gene GPNMB
Other Names HGFIN, NMB, PLCA3
Gene ID 10457 (human)
Background The protein encoded by this gene is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential. Two transcript variants encoding different isoforms have been found for this gene.
Storage Store at 2-8°C short term (1-2 weeks). Store at ≤ -20°C long term.Avoid repeated freeze-thaw.
Formulation Phosphate-buffered solution, pH 7.2.
Endotoxin < 1 EU/mg, determined by LAL gel clotting assay
Cat. No：GM-87688AB
Product：Anti-GPNMB hlgG2 Antibody(glembatumumab)
GM-87688AB-10 10 μg
GM-87688AB-100 100 μg
GM-87688AB-1000 1mg
Species Reactivity Human;
Clone glembatumumab
Source/Isotype Monoclonal human IgG2, κ
Application Bioactivity-ELISA
Specificity Detects GPNMB
Gene GPNMB
Other Names HGFIN, NMB, PLCA3
Gene ID 10457 (human)
Background The protein encoded by this gene is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential. Two transcript variants encoding different isoforms have been found for this gene.
Storage Store at 2-8°C short term (1-2 weeks). Store at ≤ -20°C long term.Avoid repeated freeze-thaw.
Formulation Phosphate-buffered solution, pH 7.2.
Endotoxin < 1 EU/mg, determined by LAL gel clotting assay
