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Current position:Product Center > Antibodies > Biosimilar Antibodies > Anti-CDH6 hIgG1 Reference Antibody (Ralubio)
Anti-CDH6 hIgG1 Reference Antibody (Ralubio)
Product Info

Cat.No:GM-87478MAB

Product :Anti-CDH6 hIgG1 Reference Antibody (Ralubio)


Cat. No. & Size

GM-87478MAB-1mg / 1 mg

GM-87478MAB-5mg / 5 mg

GM-87478MAB-25mg / 25 mg

GM-87478MAB-50mg / 50 mg

GM-87478MAB-100mg / 100mg



Description

Expression System         CHO

Aggregation                   < 5% as determined by SEC-HPLC

Purity                              > 95% as determined by SDS-PAGE

Endotoxin                       < 1 EU/mg, determined by LAL gel clotting assay

Sterility                            0.2 μm Filtered

Target                              CDH6

Clone                               raludotatug

Alternative Names         CAD6; KCAD

Source/Isotype               Human IgG1(K214R/D356E/L358M), Kappa

Application                     /

Description                     CDH6, also known as K-cadherin, belongs to type II cadherin and is composed of three distinct domains, an extracellular domain (ECD) containing five cadherin sequences, a transmembrane region, and an intracellular tail. CDH6 is highly expressed in many malignant tumors (human renal cell carcinoma, ovarian cancer, thyroid cancer, cholangiocarcinoma, and small cell lung cancer), and overexpression of CDH6 protein has a worse prognosis than cases with low or no CDH6 protein expression. Therefore, it can be used to target CDH6 related small molecule drugs or monoclonal antibodies, double antibodies.

Formulation                    phosphate-buffered solution, pH 7.4.


Data

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Current position:Product Center > -- > Anti-CDH6 hIgG1 Reference Antibody (Ralubio)
classify
Anti-CDH6 hIgG1 Reference Antibody (Ralubio)
Product Info

Cat.No:GM-87478MAB

Product :Anti-CDH6 hIgG1 Reference Antibody (Ralubio)


Cat. No. & Size

GM-87478MAB-1mg / 1 mg

GM-87478MAB-5mg / 5 mg

GM-87478MAB-25mg / 25 mg

GM-87478MAB-50mg / 50 mg

GM-87478MAB-100mg / 100mg



Description

Expression System         CHO

Aggregation                   < 5% as determined by SEC-HPLC

Purity                              > 95% as determined by SDS-PAGE

Endotoxin                       < 1 EU/mg, determined by LAL gel clotting assay

Sterility                            0.2 μm Filtered

Target                              CDH6

Clone                               raludotatug

Alternative Names         CAD6; KCAD

Source/Isotype               Human IgG1(K214R/D356E/L358M), Kappa

Application                     /

Description                     CDH6, also known as K-cadherin, belongs to type II cadherin and is composed of three distinct domains, an extracellular domain (ECD) containing five cadherin sequences, a transmembrane region, and an intracellular tail. CDH6 is highly expressed in many malignant tumors (human renal cell carcinoma, ovarian cancer, thyroid cancer, cholangiocarcinoma, and small cell lung cancer), and overexpression of CDH6 protein has a worse prognosis than cases with low or no CDH6 protein expression. Therefore, it can be used to target CDH6 related small molecule drugs or monoclonal antibodies, double antibodies.

Formulation                    phosphate-buffered solution, pH 7.4.


Data

image.png


image.png


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