Cat. No：GM-88283AB
Product：Anti-CNTN4 hIgG4 Antibody(hAb-1)
Cat. No：GM-88283AB
Product：Anti-CNTN4 hIgG4 Antibody(hAb-1)
GM-88283AB-10 10 μg
GM-88283AB-100 100 μg
GM-88283AB-1000 1mg
Species Reactivity | Human, Cynomolgus |
Clone | hAb-1 |
Source/Isotype | Human hIgG4(S228P), Lambda2 |
Application | Flow Cytometry |
Target | Detects CNTN4 |
Gene | CNTN4 |
Other Names | AXCAM, BIG-2 |
Gene ID | 152330 (Human), 9541 (Cynomolgus) |
Background | CNTN4 (Cntn4) gene plays an important role in neural development and the establishment of neural networks, mainly by functioning through signaling and axon guidance pathways within the cell adhesion molecule family. Its pathway mechanisms involve networks of cell–cell adhesion molecules, interactions with the extracellular matrix, and the targeting and stabilization of synapses between neurons, influencing neuronal migration, axon guidance, dendrite morphology, and synapse formation and plasticity. In terms of expression significance, CNTN4 is highly expressed in specific regions of both the central and peripheral nervous systems, suggesting a key role in neuronal differentiation, network assembly, and information transmission efficiency; dysregulated expression and associations with various neurodevelopmental disorders, autism spectrum disorders, and certain epilepsies or psychiatric diseases are increasingly reported, underscoring its clinical relevance as a potential diagnostic biomarker and therapeutic target. |
Storage | Store at 2-8℃ short term (1-2 weeks).Store at ≤ -20℃ long term. Avoid repeated freeze-thaw. |
Formulation | Phosphate-buffered solution, pH 7.2-7.4. |
Endotoxin | < 1 EU/mg, determined by LAL gel clotting assay |
Cat. No：GM-88283AB
Product：Anti-CNTN4 hIgG4 Antibody(hAb-1)
GM-88283AB-10 10 μg
GM-88283AB-100 100 μg
GM-88283AB-1000 1mg
Species Reactivity | Human, Cynomolgus |
Clone | hAb-1 |
Source/Isotype | Human hIgG4(S228P), Lambda2 |
Application | Flow Cytometry |
Target | Detects CNTN4 |
Gene | CNTN4 |
Other Names | AXCAM, BIG-2 |
Gene ID | 152330 (Human), 9541 (Cynomolgus) |
Background | CNTN4 (Cntn4) gene plays an important role in neural development and the establishment of neural networks, mainly by functioning through signaling and axon guidance pathways within the cell adhesion molecule family. Its pathway mechanisms involve networks of cell–cell adhesion molecules, interactions with the extracellular matrix, and the targeting and stabilization of synapses between neurons, influencing neuronal migration, axon guidance, dendrite morphology, and synapse formation and plasticity. In terms of expression significance, CNTN4 is highly expressed in specific regions of both the central and peripheral nervous systems, suggesting a key role in neuronal differentiation, network assembly, and information transmission efficiency; dysregulated expression and associations with various neurodevelopmental disorders, autism spectrum disorders, and certain epilepsies or psychiatric diseases are increasingly reported, underscoring its clinical relevance as a potential diagnostic biomarker and therapeutic target. |
Storage | Store at 2-8℃ short term (1-2 weeks).Store at ≤ -20℃ long term. Avoid repeated freeze-thaw. |
Formulation | Phosphate-buffered solution, pH 7.2-7.4. |
Endotoxin | < 1 EU/mg, determined by LAL gel clotting assay |
