| Species Reactivity | Human; Cynomolgus |
| Clone | Ts29.2 |
| Source/Isotype | Monoclonal Mouse IgG2b/κ |
| Application | Flow cytometry；Bioactivity-ELISA |
| Specificity | Detects TSPAN8 |
| Gene | TSPAN8 |
| Other Names | TM4SF3 |
| Gene ID | P19075 (human), G7PI18(Cynomolgus) |
| Background | TSPAN8 (Tetraspanin 8) is a Protein Coding gene. Diseases associated with TSPAN8 include Pancreas, Annular and Diabetes Mellitus. Among its related pathways are Extracellular vesicle-mediated signaling in recipient cells and 11p11.2 copy number variation syndrome. Tetraspanin-8, encoded by the TSPAN8 gene, is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. It is a cell-surface glycoprotein that complexes with integrins. TSPAN8 is involved in various signaling pathways, including those related to extracellular vesicle-mediated signaling in recipient cells and 11p11.2 copy number variation syndrome. Additionally, TSPAN8 is associated with diseases such as Pancreas, Annular and Diabetes Mellitus. Its role in mediating signal transduction events contributes to the regulation of cell development, activation, growth, and motility. Furthermore, TSPAN8 is expressed in different carcinomas, indicating its potential relevance in cancer biology. |
| Storage | Store at 2-8℃ short term (1-2 weeks). Store at ≤ -20℃ long term. Avoid repeated freeze-thaw. |
| Formulation | Phosphate-buffered solution, pH 7.2-7.4 |
| Endotoxin | < 1 EU/mg, determined by LAL gel clotting assay |
| Species Reactivity | Human; Cynomolgus |
| Clone | Ts29.2 |
| Source/Isotype | Monoclonal Mouse IgG2b/κ |
| Application | Flow cytometry；Bioactivity-ELISA |
| Specificity | Detects TSPAN8 |
| Gene | TSPAN8 |
| Other Names | TM4SF3 |
| Gene ID | P19075 (human), G7PI18(Cynomolgus) |
| Background | TSPAN8 (Tetraspanin 8) is a Protein Coding gene. Diseases associated with TSPAN8 include Pancreas, Annular and Diabetes Mellitus. Among its related pathways are Extracellular vesicle-mediated signaling in recipient cells and 11p11.2 copy number variation syndrome. Tetraspanin-8, encoded by the TSPAN8 gene, is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. It is a cell-surface glycoprotein that complexes with integrins. TSPAN8 is involved in various signaling pathways, including those related to extracellular vesicle-mediated signaling in recipient cells and 11p11.2 copy number variation syndrome. Additionally, TSPAN8 is associated with diseases such as Pancreas, Annular and Diabetes Mellitus. Its role in mediating signal transduction events contributes to the regulation of cell development, activation, growth, and motility. Furthermore, TSPAN8 is expressed in different carcinomas, indicating its potential relevance in cancer biology. |
| Storage | Store at 2-8℃ short term (1-2 weeks). Store at ≤ -20℃ long term. Avoid repeated freeze-thaw. |
| Formulation | Phosphate-buffered solution, pH 7.2-7.4 |
| Endotoxin | < 1 EU/mg, determined by LAL gel clotting assay |
