Cat.No：GM-86543AB
Product：Anti-c-Kit(CD117) hIgG1 Antibody(briquilimab)
Cat.No：GM-86543AB
Product：Anti-c-Kit(CD117) hIgG1 Antibody(briquilimab)
GM-86543AB-10 10 μg
GM-86543AB-100 100 μg
GM-86543AB-1000 1 mg
Species Reactivity Human; Cynomolgus
Clone briquilimab
Source/Isotype Monoclonal human IgG1, κ
Application Flow cytometry; Bioactivity-ELISA
Specificity Detects c-Kit(CD117)
Gene c-Kit(CD117)
Other Names C-Kit, CD117, MASTC, PBT, SCFR
Gene ID 3815 (human); 102137242 (Cynomolgus)
Background c-Kit, also known as CD117, is an important cell surface protein expressed in stem cells and various types of mature cells in humans and other animals. Encoded by the c-Kit gene, the c-Kit protein plays a role in cell proliferation, differentiation, and survival by binding with the cytokine SCF (stem cell factor). Mutations and abnormal expressions of the c-Kit gene have been associated with various diseases including tumors, cardiovascular diseases, and immune system disorders. Research on the c-Kit gene can aid scientists in better understanding its functions in cell biology and pathophysiology, offering new insights for diagnosis and treatment of related diseases.
Storage Store at 2-8℃ short term (1-2 weeks).Store at ≤ -20℃ long term. Avoid repeated freeze-thaw.
Formulation Phosphate-buffered solution, pH 7.2.
Endotoxin < 1 EU/mg, determined by LAL gel clotting assay
Cat.No：GM-86543AB
Product：Anti-c-Kit(CD117) hIgG1 Antibody(briquilimab)
Cat.No：GM-86543AB
Product：Anti-c-Kit(CD117) hIgG1 Antibody(briquilimab)
GM-86543AB-10 10 μg
GM-86543AB-100 100 μg
GM-86543AB-1000 1 mg
GM-86543AB-10 10 μg
GM-86543AB-100 100 μg
GM-86543AB-1000 1 mg
Species Reactivity Human; Cynomolgus
Clone briquilimab
Source/Isotype Monoclonal human IgG1, κ
Application Flow cytometry; Bioactivity-ELISA
Specificity Detects c-Kit(CD117)
Gene c-Kit(CD117)
Other Names C-Kit, CD117, MASTC, PBT, SCFR
Gene ID 3815 (human); 102137242 (Cynomolgus)
Background c-Kit, also known as CD117, is an important cell surface protein expressed in stem cells and various types of mature cells in humans and other animals. Encoded by the c-Kit gene, the c-Kit protein plays a role in cell proliferation, differentiation, and survival by binding with the cytokine SCF (stem cell factor). Mutations and abnormal expressions of the c-Kit gene have been associated with various diseases including tumors, cardiovascular diseases, and immune system disorders. Research on the c-Kit gene can aid scientists in better understanding its functions in cell biology and pathophysiology, offering new insights for diagnosis and treatment of related diseases.
Storage Store at 2-8℃ short term (1-2 weeks).Store at ≤ -20℃ long term. Avoid repeated freeze-thaw.
Formulation Phosphate-buffered solution, pH 7.2.
Endotoxin < 1 EU/mg, determined by LAL gel clotting assay
Species Reactivity Human; Cynomolgus
Clone briquilimab
Source/Isotype Monoclonal human IgG1, κ
Application Flow cytometry; Bioactivity-ELISA
Specificity Detects c-Kit(CD117)
Gene c-Kit(CD117)
Other Names C-Kit, CD117, MASTC, PBT, SCFR
Gene ID 3815 (human); 102137242 (Cynomolgus)
Background c-Kit, also known as CD117, is an important cell surface protein expressed in stem cells and various types of mature cells in humans and other animals. Encoded by the c-Kit gene, the c-Kit protein plays a role in cell proliferation, differentiation, and survival by binding with the cytokine SCF (stem cell factor). Mutations and abnormal expressions of the c-Kit gene have been associated with various diseases including tumors, cardiovascular diseases, and immune system disorders. Research on the c-Kit gene can aid scientists in better understanding its functions in cell biology and pathophysiology, offering new insights for diagnosis and treatment of related diseases.
Storage Store at 2-8℃ short term (1-2 weeks).Store at ≤ -20℃ long term. Avoid repeated freeze-thaw.
Formulation Phosphate-buffered solution, pH 7.2.
Endotoxin < 1 EU/mg, determined by LAL gel clotting assay
